PARTNER SEARCH NMP7-EU-SMCP-6, Lussemburgo.  

ricerca partner proveniente da un centro di
ricerca di Lussemburgo e finalizzata alla partecipazione al 7PQ, Tema
Nanoscienze, Nanotecnologie, Materiali e Nuove Tecnologie di
Produzione, topic NMP-2008-1.1-1 "Converging sciences and
technologies" (nano, bio, info, cogni).

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------- PARTNER SEARCH NMP7-EU-SMCP-6 --------
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<Reference n.: NMP7-EU-SMCP-6>
<Deadline: 22/02/2008>
<Programme: NMP>
<Project Title: Biosensors based on porous silicon for cancer
diagnostics.>
<Financial Scheme: SMALL OR MEDIUM - FOCUSED RESEARCH PROJECTS>

<Description: This project aims to use porous silicon for elaboration
of biosensor dedicated to cancer diagnostics. Porous silicon has
several advantages due to the nanometer size of its silicon skeleton:
emission of light in the visible spectrum and very large specific
area. Moreover it is a biocompatible material. The first objective of
this project is to improve the photoluminescence of the porous silicon
by implantation or deposition of Se or rare earth elements in order to
improve the sensor sensitivity. The second objective is to
functionalise the porous silicon with biological molecules to get a
necessary selectivity to the detection of the molecules linked with
cancer diagnostics. Plasma and chemical functionalisation will be
studied and compared for their efficiency to detect the specific
researched molecules. The development of the most appropriated devices
using optical components will constitute the third objective. The
sensor should permit the detection in blood or other biological media
of several molecules linked with the cancer. These molecules could be
molecules directly linked with cancer development (telomerase, ras
gene, nitrosamine), carcinogenic toxin from food (aflatoxin) or even
concentration of anticancer molecules (C and E vitamins, lycopene,
catechin) for a complete diagnostics. The last part of the project
consists in testing the sensor in real conditions with cancer
specialists and to implement it on portable Lab-on-Chip diagnostic
devices.>
<Organisation Type: Centro di Ricerca>
<Partner Sought: Partners seeked for: - Elaboration of porous silicon
for enhanced photoluminescence properties - Development of sensor
based on porous silicon - Functionalization for grafting of biological
molecules - Detection of molecules linked with cancer development -
Development of biosensors for medical applications -  End-user for
manufacturing biosensors and portable Lab-on-Chip Diagnostic devices,
development of products with cancer diagnostics features - Company
interested by the market of Point-of-Care (PoC) Diagnostics.>